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A growing number of countries that had lifted COVID-19 restrictions are now reimposing them as cases surge.
The Singaporean government has said unvaccinated people "disproportionately contribute" to the strain on the country's healthcare resources.
Costa Rica has become the first country in the world to make Covid-19 vaccinations mandatory for children.
The jab will join the extensive list of basic childhood vaccinations already required by law, health officials said.
The country signed a deal with Pfizer to acquire doses to start vaccinating all under-12s from March 2022.
Big Bird has been accused of being a "communist" and promoting "government propaganda" after the character tweeted about getting a COVID-19 vaccine.
Travellers are facing long queues at US borders as international travel resumes for the first time in the United States after more than a year and a half.
Europe is once again "at the epicentre" of the Covid pandemic, the World Health Organization (WHO) has warned, as cases soar across the continent.
At a press conference WHO Europe head Hans Kluge said the continent could see half a million more deaths by February.
He blamed insufficient vaccine take-up for the rise.
A pill to treat Covid developed by the US company Pfizer cuts the risk of hospitalisation or death by 89% in vulnerable adults, clinical trial results suggest.
WHO head Tedros Adhanom Ghebreyesus says no more COVID-19 jabs should go to countries that have more than 40 per cent of its population vaccinated.
University of Oxford scientists have uncovered a gene that doubles the risk of lung failure and death from Covid.
They say 60% of people from South Asian backgrounds and 15% of people of European ancestry carry the high-risk version of the gene.
As more countries open up to international travellers, vaccine equity continues to be a problem in Africa and in developing countries.